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Peripheral nerve injury

Peripheral nerve injury is caused by a variety of reasons, mainly characterized by symmetric sensory deprivation of the distal limbs or unilateral loss of movements and vegetative nerve functional disturbance.

Etiology: Peripheral nerve injury may mostly occur during the fracture-related stab, the stretch of dislocated limbs, excessive entrapment or compression of external fixation following fractures, replantation of limbs, knife injury, soft tissue injury-induced nerve adhesion, spinal nerve root compression, bone degeneration-induced crushed nerve injury and blood-supplying insufficiency of limbs, with the type of spinal nerve root, brachial plexus, median nerve, ulnar nerve, radial nerve, sciatic nerve, femoral nerve, common peroneal nerve, tibial nerve and digital nerve injuries.

Motor disorder: The disease is characterized by decrease of muscular strength, hypotonia, and diminished or disappeared tendon reflexes. Muscular atrophy of limbs, mainly in the distal ones, may occur in late stage.

Vegetative nerve functional disturbance: The main manifestations of this disease include coldness in acral skin, symmetric paresthesia, pallor, cyanochroia, numbness or dyshidrosis, pain, hypersensitivity, hypoesthesia, limb deformities, pachylosis and skin thinning, and glove distribution of sensory loss.

Peripheral nerve injury associated with limbs disturbance accounts for 12.5% of all nerve injuries. It primarily affect human nerve sheath and is one less serious nerve injury. When peripheral nerve is not completely ruptured, surgery is unnecessary. As long as the correct treatment is given, most of them can fully recover. Surgical treatment is necessary only when complete rupture occurs. However, surgery may lead to a new trauma. Some patients are so impatient as to undergo surgical treatment in the effective self-recovery period, but eventually lead to a poor outcome. This is caused by endplate scar formation at the attached site which makes nerve cells and fibers not cross the injured site and leads to an irreparable loss for the recovery of limb functions following nerve injuries. From the perspective of treatment, the patients should be aggressively treated regardless of the results of surgical treatment. Once ischemic neuronal degeneration secondary to the disease occurs, the recovery will be hopeless.

The timing of treatment for the disease is rigorous. If the treatment is delayed for 1 to 2 years, the injured nerve fibers would be completely replaced by scar tissue, which eventually lead to severe disability. And the recovery of nerve function is also extremely difficult even if a second surgery for neural transplantation can be carried out.

Our hospital has broken the therapeutic theory of traditional Chinese and Western medicine and make use of “Spinal Nerve Regeneration Dan”, the technology achievement protected by national patent laws, to supply sufficient blood to the local microcirculation of injured nerve, activate paralytic and shocked nerves following injury, enhance nerve impulse conduction across the injured endplate and realize the regeneration of nerve cells, all which can lead to the recovery of functions that dominate and regulate limb movement as well as other functions.

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