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Typical cases: “Spinal Nerve Regeneration Dan” for brain & spinal cord injury with paraplegia

Case One: Du Qin-xi, a 36-year-old female, underwent compression fractures of C6&7 in a road accident. The patient was admitted to a Grade 3 Class A hospital in Daqing City and MRT revealed spinal cord contusion with porosis. As is shown in Figure 1, spinal cord was purple with no beats and paraplegic index of 6th grade (complete paralysis and loss of various neurological functions below injured level).  

Diagnostic conclusion: Compression fractures of C6&7, grade II fracture, grade II dislocation with spinal cord injury, urinary and defecation incontinence, and paraplegic index of 6th grade (complete paralysis and loss of various neurological functions below the injured level).

Course of treatment: The patient was treated with oral "Spinal Nerve Regeneration Dan" 3.6 g 3/d for 3 months (equivalent to 3 courses of treatment). And physical examination revealed that grade II and III of muscle strength in left and right upper limbs, respectively. Fingers function was greatly recovered. The muscle strength of left and right lower limbs was grade I and 0, respectively. The muscle strength was recovered to grade II~III. After 9 more months of treatment (equivalent to 9 courses, 4.5 g 3/d, orally), the lower limb function were also recovered and the patient could walk with the aid of crutches, with the muscle strength of grade III~VI.

  Case Two: Wu Xiao-feng, an 18-year-old girl student, underwent comminuted fractures of T12&L1 in a road accident. The patient was admitted to a Grade 3 Class A hospital in Xi’an and MRT revealed complete spinal cord transection. As is shown in Figure 3, it was empty below the dura of spinal cord, and the injured spinal cord was purple with no beats and paraplegic index of 6th grade (complete paralysis and loss of motor function, urinary and defecation incontinence, and sensory deprivation below the injured level).  

Diagnostic Conclusion: Comminuted fractures of T12&L1, grade VI fracture, grade VI dislocation with spinal cord injury. Physical examination revealed paraplegic index of 6th grade and severe muscular atrophy.

Course of treatment: The patient was treated with oral "Spinal Nerve Regeneration Dan" 3.6 g 3/d for 4 months (equivalent to 4 courses of treatment). And physical examination revealed that muscle strength of left lower limbs was recovered to grade III and right lower limbs to grade II. Urinary and defecation function could be basically controlled. The patient could walk with the aid of crutches. After 9 more months of treatment (equivalent to 9 courses, 4.5 g 3/d, orally), the muscle strength of lower extremities was recovered to grade IV~V, the patient could walk with single crutch and urinary and defecation function was totally recovered. Figure 4 reveals the regeneration of nerve fibers on MRT. Follow-up after 8 years showed the patient could walk 2~3 kilometers without any help. Now she has graduated with Master’s degree and participated in work.

  Case Three: Yang Fang, a female, underwent comminuted fractures of L1 in a road accident. The patient was admitted to the Worker's Hospital of Qingyang Oilfield and MRT revealed 80% of compression on conus medullaris (Figure 8). During the surgery, severe breakage of cauda equine (peripheral nerve) could be observed, with paraplegic index of 5th grade (complete paraplegia below level of the fold inguen, urinary and defecation incontinence, and mild muscular atrophy).  

Diagnostic Conclusion: Comminuted and blowout fractures of L1, grade III fracture with conus medullaris injury, urinary and defecation incontinence with spasms, and paraplegic index of 5th grade (complete paralysis and loss of various neurological functions below the injured level).

Course of treatment: The patient was treated mainly with oral "Spinal Nerve Regeneration Dan", with 0.9 g (0.3 g per pill) 3/d during the first course and 3.6 g/d during the second course. After three months (one course), urine and defecation had already been perceived, but was not yet controlled. Physical examination showed grade III of muscular strength in lower extremities. The patient could walk unsteadily with the aid of crutches. After 6 more months of treatment (2 courses), the patient could walk with grade V of muscular strength in lower extremities. Follow-up after 2 years showed the patient had recovered basically with grade V of muscular strength in lower extremities, apart from perineal bearing-down pain during urination.

 

Bone Injury and Disease Hospital, Xinjiang Country, China

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Affiliated Hospital, North Academy of Traditional Chinese Medicine, Shaanxi China

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